In Milan, you could try the Hotel Rovello
(V.Rovello 18, tel. 02/86-46-46-54.)
Never stayed there, but have heard nice things about it.
The place I did stay was Hotel Speronari (Via Speronari 4, tel.
01/864-61125). It's really bare bones, but safe and actually quiet.
Both hotels are right near the Dumo, and very easy to get to on the
easy metro. I had no trouble getting to Malpensa the next day.
Speronari has one great thing going for it: it's right around the
corner from the most outrageous pastry shop/bakery imaginable.