My wife and I spent a week in Rome, June 2001. We stayed at a nice hotel (http://www.suorebambinogesu.it/DNB/index.html) a few minutes walk from Termini.

True, the Termini district doesn't qualify as the top attraction in Rome, but to us it was very convenient living there. We bought a bus/metro ticket valid for a week (ca. 14 EU), and from Termini you can go everywhere by bus/metro. Last but not least: most buses RETURN to Termini, which is indeed nice when you're tired and want to get home fast and easy.

Regards Eric Bentzen, Denmark