Don't know what price range and amenities you desire, but we enjoyed our stay at the Hotel San Rufino in Assisi in 2001 - very reasonably priced and comfortable. It's on the upper side of the old town, by the San Rufino church. The area is fairly quiet, except for some construction underway when we were there - I believe it was repair work from the earthquake a few years previous, and is probably finished by now. Here's their web site: http://www.venere.com/it/assisi/sanrufino/

Enjoy your trip!

Cindy in Harrisonburg, VA http://sts.cmorf.com