Many Ziners have stayed in hotels in Rome and Florence - search the archive. You don't mention your budget. If you let us know your price range and the amenities you require, it would be easier to recommend hotels. For example, some people stay in convents (yes, they have double rooms!) and enjoy the peace and the lower price. Some require name brands and four or more star comforts. One bit of advice - stay as centrally as you can (not hard in Florence) in a safe neighbourhood.

Frances Toronto, Canada