I have stayed in the Majestic on the Zócalo. And I've been in the Galeria Park in the Zona Rosa.

The Majestic is in a 17th century building whereas the Galería Park is in a 20th century building.

The room we had in the Majestic was a bit worn about the edges but suited us fine. We had a simple double. I can't comment on the rooms in the Galería Park.

The Majestic has a nice roof top restaurant and terrace looking out on the Zócalo. If you do stay in the Majestic be forewarned that the rooms that look out on the Zócalo, although wonderful to enjoy the view in midday and evening, are subject to the military honor guard's ceremonial raising of the huge Mexican flag at dawn. This includes the playing of the national anthem. Not a problem if you are an early riser which we are. It is quite a spectacle. Also done in reverse in the evening. Otherwise noise was not an issue. Contrary to what you would expect the Centro Histórico is not quite as busy at night as is the Zona Rosa.

The Centro Histórico is a better location for the immediate sights within its area e.g., the Cathedral, the National Palace, and the Templo Mayor. Plus there are some interesting other points of interest, restaurants, and shops such as the Palacio de Iturbide, Casa de Azulejos, Cafe Tacuba, Hostelería de Santo Domingo, and Dulcería Celaya (mmm! mmmm!).

The Zona Rosa is replete with restaurants, cafes, and shops but nothing of historical significance. But it is centrally located.

Undoubtedly, you'll be traveling all over the city. The subway is much quicker than taxis, especially when heading into the Centro Histórico. The narrower streets make for severe traffic congestion in this area. Sometimes it can be quicker to just walk from the Alameda to the Zócalo.

The Mision Colon Reforma is on the Paseo de la Reforma at the Glorieta Colón about midway between the Zona Rosa and the Alameda. Kind of between the other two hotels. The Reforma is the major street in Mexico City. This is a central location.

Got to run but I've got plenty more help for you. Any specific questions?

John in San Diego and envious of your visit to chilangolandia.